Monoclonal Antibodies in Clinical Medicine

Monoclonal antibodies in clinical medicine.

Monoclonal Antibodies

SUMMARY Monoclonal Antibodies are identical antibodies and Can be generated in ultimated amounts by countinuos cultures of single antibody- secreting cells. These cell lines are produced by cell fusion of normal lymphocytes to cells of a myeloma tumor cell line, which confers on the antibody producing hybrid cell, immortality and the ability grow as atumor in animals. monoclonal antibodies c...

Monoclonal antibodies in nuclear medicine.

Monoclonal antibodies have been a part of biomedical research for nearly a decade, yet a comparable period of time may be required before radiolabeled monoclonal antibodies come into standard practice in the diagnosis and therapy of human disease. Difficulties in identifying appropriate antigens, developing the optimal antibody species, attaching the most effective radiolabel and choosing the b...

Monoclonal Antibodies in Medicine— Today and Tomorrow

Ever since Köhler and Milstein in 1975 discovered the technique of production of monoclonal antibodies (MoAb) in vitro, it has become all pervasive in every field of medicine and other scientific areas. Be it diagnostic, prognostic or therapeutic areas, MoAbs continue to play a central role and evolve. As immunology is the basis of our survival, MoAbs help us in diagnosing, prognosticating and ...

Monoclonal Antibodies: A tool in clinical research

Indian Journal of Clinical Medicine 2013:4 9 Abstract: Monoclonal antibodies (MAbs) are an old immunological tool with applications in the fields of immunology, biotechnology, biochemistry, and applied biology. Production of monoclonal antibodies using hybridoma technology was discovered in 1975 by Georges Kohler of West Germany and Cesar Milstein of Argentina. Modern-day research on MAbs from ...